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Many research studies have demonstrated that most people require a minimum of 10 mg vitamin C per day in order to prevent scurvy. In the EU the Daily Reference Intake (RI) for an adult person is 80 mg Vitamin C. Smokers, pregnant women and breast feeding women are generally recommended to take more, up to 100 mg per day. A daily intake of 80 mg vitamin C creates a vitamin C storage in the body which protects it against scurvy for 30 to 45 days, if no more uptake takes place.

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The optimal amount of vitamin C

The optimal amount of vitamin C necessary to completely meet the demands of the body is difficult to estimate. It is interesting to note, that nearly all animals are capable to produce vitamin C. Exceptions are, in addition to humans, the ape family, the guinea pig, the rainbow trout and the coho salmon.

Table 1 shows that the vitamin C production of animals can vary greatly. When severely stressed, goats produce six times as much vitamin C compared to under non-stressed conditions. In the case of rabbits, about 25 times as much vitamin C is produced under stress.

Converting the values shown in Table 1 to an average 75 kg adult person would lead to the conclusion, under normal circumstances adults would require a daily intake of 0.4 – 3 grams of vitamin C to meet the bodily production of animals. Under stress, humans would require as much as 3 – 17 grams of vitamin C to meet the bodily production of stressed animals.

Table 1: Vitamin C-production in warm blooded animals




Vitamin C Production

(mg/kg body weight /day)
Species Low amount High amount
(No stress) (severe stress)
Goat 33 190
Sheep 25 not available
Rat 39 199
Mouse 34 275
Rabbit 9 226
Cat 5 40
Dog 5 40
Human (RDA) 0.9

 Based on the eating behavior of large apes, two-time Nobel Prize winner Linus Pauling recommends human adults to take 2.3 – 10 grams of vitamin C daily.

Ester C Vitamin: The Solution to Limitation in Uptake?

Research has shown, there is a limit to the amount of vitamin C a human body can digest, when taken orally. These limits are not fixed, there are indications the vitamin C tolerance of the body increases when a person gets ill, similar to the way the Vitamin C production increases in animals that are ill or under severe stress.

Ester C Vitamin is absorbed faster than ‘normal’ vitamin C, leads to ascorbic acid concentrations in human blood serum that on average are twice as high, and stays in the body twice as long. Putting this all together, these data suggest Ester C Vitamin may be up to four times as powerful compared to ‘normal’ vitamin C.

Ester C Vitamin may be a simple and effective way to overcome the limitations in vitamin C uptake. A daily consumption of 1 gram Ester C Vitamin per day would be comparable to an uptake of 4 gram ‘normal’ vitamin C, and bring the vitamin C consumption in the range as advised by Nobel Price winner Linus Pauling.

Daily consumption of 1 gram Ester C Vitamin is generally considered as safe. Several independent authorities such as the UK Expert Group on Vitamins and Minerals and the Food and Nutrition Board, have set the Maximum Safe Dose of vitamin C at 2 grams per day.

Ester-C® is a registered trademark of The Ester-C Company

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how much ester c vitamin does a human need?


Do you have questions about Ester C vitamin? Contact Kala Health or view our product information. You can reach us via our telephone number +31 703450290 or our e-mail address

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